It is found that the fractions of resting memory CD4 T cells, M1 macrophages, resting dendritic cells, resting mast cells, monocytes, and eosinophils in HNSCC tissues are associated with HNSCC progression, while lower infiltration of memory CD4 T cells would lead to worse prognosis [12]. The gene discussed is CD4; the disease is head and neck squamous cell carcinoma.