In our study, MM cells transfected with miR-29c-3p-mimcs or si-CDCA4 exhibited protein expression unfavorable to MM progression, that is, the expressions of Bax, Caspase3, and E-cadherin proteins were remarkably elevated and those of Bcl-2, N-cadherin, and vimentin were remarkably suppressed. This evidence concerns the gene CDH2 and Miyoshi myopathy.