In both genetically engineered mouse models and xenograft models, lncRNA MALAT1 overexpression inhibits, while MALAT1 deficiency induces breast cancer metastasis, which is reversed by re-expression of MALAT1, suggesting that MALAT1 is a metastasis-suppressing lncRNA (Kim et al., 2018). The gene discussed is MALAT1; the disease is breast cancer.