We then checked the expression of the canonical cell-type markers: cancer/epithelial cell marker genes (Cdh1, Krt18, and Krt5); mesenchymal cell marker genes (Col1a1, Col1a2, and Col3a1); immune cell marker genes (Ptprc, Cd68, and Csf1r); and endothelial cell marker genes (Pecam1, Emcn, and Cdh5) (Supplementary Figure 1F). The gene discussed is KRT5; the disease is cancer.