Neuroprotective effects of CBD have also been shown following anti-Yo-associated paraneoplastic cerebellar degeneration, where data indicate that CBD minimizes the downgrading of the mitochondrial membrane potential induced by anti-Yo in a manner similar to the ROS scavenger butylated hydroxytoluene, although simultaneously potentiated Yo-induced ROS production [203]. Here, CDR2 is linked to cerebellar degeneration.