Our data suggested that CCNB2, CCNB1, PLK1, TTK, CDC20, BUB1, PTTG1, CDC45, BUB1B, CDC25C, CCNA2, and AURKA were remarkably upregulated in PCa cell lines relative to that in normal prostate cell line WPMY-1. The gene discussed is CDC25C; the disease is posterior cortical atrophy.