Our data suggested that CCNB2, CCNB1, PLK1, TTK, CDC20, BUB1, PTTG1, CDC45, BUB1B, CDC25C, CCNA2, and AURKA were remarkably upregulated in PCa cell lines relative to that in normal prostate cell line WPMY-1. This evidence concerns the gene PLK1 and posterior cortical atrophy.