Additionally, we found cell cycle regulators, containing CCNB2, CCNB1, PLK1, TTK, CDC20, BUB1, PTTG1, CDC45, BUB1B, CDC25C, CCNA2, and AURKA, were apparently overexpressed and had a correlation with shorter time of DFS in PCa. Here, CDC45 is linked to posterior cortical atrophy.