Among various other genomic alterations, the most common one is the point mutation in chromosome 7 c.74146970T > A of the general transcription factor II-I (GTF2I) gene that has been identified to be specific to thymic epithelial tumours, predominantly in type A and AB thymomas and associated with a more favourable prognosis(7, 8). The gene discussed is GTF2I; the disease is thymoma.