UCHL1 and neoplasm: Ubiquitin Carboxy-Terminal Hydrolase L1 (UCHL1) is a member of the UCH family of DUBs that is expressed in varied amounts across tissues and tumours, from being among the most abundant proteins in the brain [24–28] to undetectable levels in nasopharyngeal, gastric, colorectal, renal cells and ovarian carcinomas [29–32].