H2AX and renal cell carcinoma: After successful transfection of miR-328-3p mimic or inhibitor in RCC cell lines (Figure 5B), we found that ectopic expression of miR-328-3p inhibited, while knockdown of miR-328-3p markedly increased, the mRNA (Figure 5C) and protein (Figure 5D) expression levels of H2AX.