CCN5 and neoplasm: While, in nude mouse models, subcutaneous tumour growth after 4 weeks did not differ in mice injected with Hep3B-WISP2 and Hep3B-Vector (1.23 ± 0.15 mm vs. 1.33 ± 0.12 mm, p = 0.2354; Figure 3A, 3a).