Cell cycle proteins (CDK1, Cyclin D1, CDK6, Cyclin E2) were significantly reduced upon circMYH9 knockdown (Fig. 2F, Figure S1P), whereas cell cycle was promoted and cell cycle proteins were increased after circMYH9 overexpression in CRC cells (Fig. 2G, H, Figure S1Q). Here, CCNE2 is linked to colorectal carcinoma.