In the Oncomine database, lower XDH mRNA expression was detected in bladder cancer, breast cancer, colorectal cancer, leukemia, liver cancer, and lymphoma (Fig. 1A), while higher mRNA expression of XDH was observed in head and neck cancer (HNSC) and lung cancer in some datasets compared to that in normal tissues. The gene discussed is XDH; the disease is urinary bladder cancer.