In particular, in relation to the number of tumour lesions, the AFP-specific T cell response was significantly stronger in patients with multiple lesions (201.75 ± 78.65 SFUs/106 cells) than that in patients with solitary tumour lesions (13.35 ± 4.42 SFUs/106 cells, P = 0.0072; Fig. 5D). The gene discussed is AFP; the disease is neoplasm.