Also, the univariate analysis found that hypertension, APACHE II score, SOFA score, CCI, phosphate, MAP, mechanical ventilation, Hb, Cr, and GFR were associated with short-term and medium-term prognosis of critically ill AKI patients with CRRT, while BMI was only associated with 90-day mortality. The gene discussed is GSTM1; the disease is acute kidney injury.