In patients with metabolic acidosis, the risks of 28-day and 90-day mortality decreased with the increasing albumin, and the adjusted HR (95% CI) was 0.24 (95% CI 0.11–0.51, p < 0.001) and 0.28 (95% CI 0.15–0.53, p < 0.001), respectively (Table 5). The gene discussed is ALB; the disease is metabolic acidosis.