We found that ZEB1 is downregulated in TP53-mutated tumours and not changed in CTNNB1 mutations, whereas ZEB2 was upregulated in tumours with CTNNB1 mutation and not changed in TP53-mutated tumours (Fig. S7D), further supporting that the ZEBs often have a contrasting expression pattern. The gene discussed is ZEB1; the disease is neoplasm.