PQ- and TQ-induced AH is a major concern for malaria control programmes, especially in the more severe SE Asian G6PD variants like Viangchan (a WHO Class II variant)[14] because reducing the substantial burden of vivax malaria requires attacking its hypnozoite reservoir with PQ or TQ; indeed, hypnozoites are the dominant (>80%) source of recurrent vivax infections (relapses)[15]. This evidence concerns the gene G6PD and malaria.