EPHA2 and cataract: In order to determine whether Epha2 heterozygous-null mice develop cataract with increase in age, different groups of 11, 18, 27, 38, 45, and 52 weeks old Epha2 wild-type (Epha2+/+) and Epha2+/− mice on C57BL/6J background were examined for lens opacity.