Mice depleted with neutrophils suffer severe disease in DSS-induced colitis,48,49 and lysophosphatidylserine (LysoPS) released by apoptotic neutrophils promotes ILC3 production of IL-22, leading to promoting tissue repair in DSS-induced colitis.48 These data suggest that neutrophils participate in tissue repair and the maintenance of mucosal homeostasis. Here, IL22 is linked to colitis.