HDAC1 expression does not differ significantly across the 3 molecular subgroups of GBM (ref. 30 and Figure 1C), and its expression was higher in GBM compared with normal brain tissue (Supplemental Figure 1A; supplemental material available online with this article; https://doi.org/10.1172/jci.insight.149232DS1). Here, HDAC1 is linked to glioblastoma.