Hence, we propose that the presence of AREs at the third exon may act as a putative enhancer region in the transcriptional regulation of DLX1. We further examined the binding of AR on the DLX1 gene using publicly available dataset (GSE70079)45 comprising normal and PCa specimens, and a remarkable enrichment of AR was observed on the putative enhancer element of the DLX1 in PCa specimens (Fig. 5i). This evidence concerns the gene AR and posterior cortical atrophy.