Subsequent gene set enrichment analysis (GSEA) showed enrichment of genes involved in the apoptotic pathway in DLX1-KO cells, whereas gene sets involved in epithelial-to-mesenchymal transition (EMT), cancer stemness, active Akt, and Wnt signaling were enriched in the control cells (Fig. 1l, m). The gene discussed is AKT1; the disease is cancer.