PHOX2B and neuroblastoma: In contrast, the transcriptional profile of the clusters identified in low-risk neuroblastoma did not resemble the human progenitor population identified in postnatal gland, instead they showed a noradrenergic (NOR) transcriptional signature (i.e., NTRK1, CHGA, CHGB, DBH, TH, and PHOX2B) matching the transcriptome of human and mouse postnatal chromaffin cells, as well as fetal human (8–14 PCW) and mouse embryonic (E13) sympathoblast and chromaffin populations.