Previous researches have shown that the expression level of SRGN is up-regulated in many tumors, which contributes to tumor growth and metastasis, and is associated with poor prognosis [8, 9], including acute myeloid leukemia [10], breast cancer [11, 12], colorectal cancer [13], nasopharyngeal cancer [14, 15]. The gene discussed is SRGN; the disease is breast cancer.