In particular, COMMD2 expression was almost significantly correlated with all markers of immune cells; specifically, COMMD2 expression was closely correlated (|Correlation coefficient| > 0.4) with CD8+ T cells (CD45 (PTPRC)), M1 macrophages (IRF5), neutrophils (IRF5), DCs (IRF5), Th1 cells (IRF5), and regulatory T cells (Tregs) (CCR8, STAT5B) in HCC. Here, CD8A is linked to hepatocellular carcinoma.