ASXL1 and myelodysplastic syndrome: ASXL1 mutations were the most frequent ones, and it should be noted that the majority of t(4;12) cases (n = 12/19, 63%) in our cohort fulfilled criteria for AML with MDS‐related changes (MRC‐AML) (multilineage dysplasia, MDS‐related cytogenetic abnormalities), which harboured frequent ASXL1 mutations.27