ALKBH5 is implicated in various physiological and pathological processes including DNA damage [25], autophagy [26, 27], ferroptosis [28], innate immune response [29], brain development [30], cardiomyocyte proliferation and heart regeneration [31], ossification [32], osteogenic differentiation [33], systemic lupus erythematosus [34], diabetes [35], reproductive system diseases [36], rheumatoid arthritis [37], Hirschsprung's disease [38], recurrent miscarriage [39], and cancers [28, 40–49]. This evidence concerns the gene ALKBH5 and cancer.