To investigate the roles of SMC autophagy in the development and progression of AAA, both apoeKO mice (control) and Atg7cKO:apoeKO mice fed a standard diet at the age of 10 weeks were administered angiotensin II at 1,000 ng/kg/min by osmotic minipump for up to 4 weeks. This evidence concerns the gene AGT and triple-A syndrome.