Another interestingly recent single-cell transcriptomics study investigating temporal neutrophil diversity in the blood and heart after murine myocardial infarction indicated that all neutrophils highly expressed CXCR2, and its surface level was slightly increased in SiglecFhi vs. SiglecFlow neutrophils at day 3 (47). The gene discussed is CXCR2; the disease is myocardial infarction.