Multiple GWAS have identified common single-nucleotide variants with a MAF>5% associated with IPF in several genes that play a crucial role in different pathways related to disease pathogenesis, among which are MUC5B, FAM13A, DSP, TOLLIP, TERT, TERC, MDGA2, SPPL2C (17, 26). Here, SPPL2C is linked to idiopathic pulmonary fibrosis.