Recently, SIX6 has been found to be associated with T-cell acute lymphoblastic leukemia (T-ALL) (Laukkanen et al., 2020), though the researchers of the study concluded that SIX6 most likely belonged to a larger regulatory gene network and increased levels of SIX6 alone were not sufficient to induce development of T-ALL. Here, SIX6 is linked to T-cell acute lymphoblastic leukemia.