SIX2 has been detected in other cancers such as hepatocellular carcinoma (HCC) (Zhu et al., 2016; Li et al., 2018; Wan et al., 2019), non-small cell lung cancer (Hou et al., 2019) and colorectal cancer (Wu et al., 2017). Here, SIX2 is linked to colorectal cancer.