TFEB and renal cell carcinoma: Another phenotype of TFEB-related RCC named TFEB-amplified RCC is independent of TFEB rearrangement, which has been identified sharing feature of nuclear TFEB overexpression similar to t(6;11) RCC (Caliò et al., 2019), but occurring in older patients with a more aggressive clinical course (Argani et al., 2016).