IGF1R and familial pancreatic carcinoma: Recently developed fluorescence imaging techniques for intraoperative identification of pancreatic cancer employ 5-aminolevulinic acid (27), indocyanine green (28), novel fluorophores targeting carbohydrate antigen 19-9 (CA19-9) (29), carcinoembryonic antigen (CEA) (30–35), epidermal growth factor receptor (EGFR) (36, 37), and insulin-like growth factor 1 receptor (IGF-1R) (38).