As shown in the immunofluorescence staining results of the glioma xenograft in Figure 3D, U87Mcherry Lv-SNAP25 glioma cell-transplanted-xenograft expressed lower MAP2 expression than U87Mcherry Lv-NC group, indicating a negative function of SNAP25 in synaptic plasticity. The gene discussed is SNAP25; the disease is glioma.