We found that the expression of PD-L1 was not related to overall survival (OS, HR: 1.16, 95% CI: 0.94-1.42, <i>p</i> = 0.16) or disease-free survival (DFS, HR: 0.85, 95% CI: 0.66-1.10, <i>p</i> = 0.21) in ESCC. Here, CD274 is linked to esophageal squamous cell carcinoma.