TIGIT and acute myeloid leukemia: Previously, high expression of PD-1 and TIGIT on PB T cells from AML patients has been reported (33, 35, 36), and higher PD-1 expression also detected on BM T cells in our previous study (37); however, how the expression of TIGIT and its co-expression with PD-1 changes in the BM of de novo (DN) AML patients remains unknown.