KEGG analysis results of signal samples indicated that the five pathways were associated with the biological processes of the pro-inflammatory effects and that the metastasis process are significantly enriched, including the TNF signaling pathway, IL−17 signaling pathway, NF-kappa B signaling pathway, Transcriptional misregulation in cancer, and MAPK signaling pathway (Figures 2A–C). Here, TNF is linked to cancer.