ESR1 and cancer: glaberMuell.-Age., P. massoniana Lamb., and P. aviculare, were found to have the anti-cancer compound, Epigallocatechin-3-gallate (EGCG), which regulates EMT and CSCs in several estrogen receptors (ER)-negative breast cancer cells by downregulating ER-α36 expression (21, 81).