An analysis of the four public datasets annotated for (PAM50) molecular subtypes showed that HOXA1 was consistently most highly expressed in basal-like samples, compared to HER2 or luminal subtypes, confirming the results in Table 3, and in further support of a role for HOXA1 in breast cancer aggressiveness (Figure 1 and Supplemental Figure 1). This evidence concerns the gene HOXA1 and breast cancer.