Studies have shown that the expression of DPEP1 is reduced in invasive and in situ lobular carcinoma of the breast and pancreatic ductal adenocarcinoma (Green et al., 2009; Zhang et al., 2012) and is highly expressed in colorectal cancer and hepatoblastoma (Toiyama et al., 2011; Tachibana et al., 2017; Cui et al., 2019). Here, DPEP1 is linked to hepatoblastoma.