IL12RB1 and histoplasmosis: IL-12RB1 (interleukin 12 receptor subunit beta 1) impairs the development of human IL-17 producing T cells (Huppler et al., 2012; Johnson et al., 2012; Thompson and Orr, 2018), and mutations inherited might be responsible for histoplasmosis (León-Lara et al., 2020).