LMNA and mandibuloacral dysplasia: Finally, the morpholino downregulation of zebrafish lmna gene or the transgenic overexpression of mutant human alleles of LMNA (Koshimizu et al., 2011) has been proposed as models of mandibuloacral dysplasia, whereas the CRISPR/Cas9 editing of mmp14 (De Vos et al., 2018) has been proposed as a model of MONA syndrome.