LOF TALEN-edited or ENU-induced galnt3 mutants in zebrafish show hyperostosis and ectopic calcium deposits (Bergen et al., 2017; Stevenson et al., 2017) that resemble human hyperostosis caused by autosomal recessive mutations in GALNT3 gene (Mortier et al., 2019). The gene discussed is GALNT3; the disease is hyperostosis.