VAT ILC2s suppress harmful inflammation found in T2DM through the production of type two cytokines such as IL-5 and IL-13, which stimulate eosinophils production of IL-4 and differentiation of macrophages to anti-inflammatory state (identified as alternatively activated macrophages, AAMs, M2) in white adipose tissues (18). The gene discussed is IL13; the disease is type 2 diabetes mellitus.