As observed for PBMC, significantly enhanced production of pro-inflammatory cytokines TNFα, IL-6, and IL-15, chemokines CCL4, and CXCL11, and to a lesser extent IL-4 and IL-7 by CHD monocytes were noted (Figure 2D and Supplementary Figure 3A). The gene discussed is CXCL11; the disease is coronary artery disorder.