Cells isolated from the mediastinal lymph node had reduced proliferative capacity and had reduced production of IL-5, IL-13, IL-4, IL-6 and IL-10 relative to control mice, whereas IFN-γ production from these cells remained unchanged compared with the control, suggesting that the Th2 response, but not Th1 responses, was specifically affected by the infection with the virus (18). This evidence concerns the gene IL6 and infection.