As measured by intracellular flow cytometric staining of stimulated CD4+ T lymphocytes, PCTR1 significantly decreased interferon-gamma (IFNγ) expression compared to vehicle, as measured by IFNγ+ CD4+ T cells (1.08 ± 0.15 vs 2.82 ± 0.72 x104, p=0.029), returning expression to pre-infection baseline (Figure 5B), with a similar trend for IFNγ+ CD8+ T cells and IFNγ+ NK cells (Figures 5C, D). This evidence concerns the gene CD8A and infection.