CXCL12 levels were higher in patients with OAPS than in APL carriers (p=0.0123), patients with miscarriages (p<0.0001), patients with thrombosis (p=0.0024), and HCs (p=0.0007), but showed no differences compared to patients with RA (p=0.2510) or SLE (p=0.0791). This evidence concerns the gene CXCL12 and systemic lupus erythematosus.