This is the case for ABHD5 and ABHD12 causing Chanarin-Dorfmann (OMIM # 275630) and polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract (PHARC; OMIM # 612674) syndromes, respectively (24, 25). This evidence concerns the gene ABHD12 and retinitis pigmentosa.