MBTPS1 and goblet cell carcinoma: When compared with patients with PCC, patients with GCC had higher levels of S1P (p = 0.001, Figure 6A), and plasma S1P levels demonstrated an AUC of 0.738 (95% CI: 0.599–0.849) to differentiate patients with GCC from PCC, with 86.20% of specificity and 50.00% of sensitivity (Figure 6B).