The pathogenesis of Sjögren’s syndrome involves activation of both innate and adaptive immune pathways, e.g., B cell-activating factor (BAFF)/BAFF receptor axis, interferon (IFN) signatures, and nuclear factor kappa B (NF-kB) signaling (Sandhya et al., 2017). This evidence concerns the gene TNFSF13B and Sjogren syndrome.