In mice with αMHC-Cre mediated β-catenin deletion, which made the cells non-responsive to Wnt stimulation, the scar size after MI was smaller which was associated with enhanced differentiation of a cardiac progenitor population (marked as αMHC+/GATA4+/Tbx5+, but cTnT−) into small cTnT+ cardiomyocytes in the infarcted region32. The gene discussed is TNNT2; the disease is myocardial infarction.