CDKN1A and urinary bladder cancer: Recent studies have found that HSPA6 can enhance the inhibitory effect of garlic extract on the proliferation, migration, and invasion of bladder cancer cells by enhancing the ATM-CHK2-Cdc25C-p21 WAF1-Cdc2 cascade response and MAPK and Akt phosphorylation and inhibiting MMP-9 expression [22].