In alectinib-resistant RET fusion NSCLC cells from another patient, nivolumab or atezolizumab, either alone or in combination with alectinib, did not significant inhibit the growth of tumor cells (102 ± 11%, 75 ± 4%, 74 ± 6%, 79 ± 3%, 75 ± 9% respectively) (Fig. 8d). Here, RET is linked to neoplasm.