Several types of RNases such as Barnase, Binase, Ranpirnase, human pancreatic RNase 1 (HP-RNase 1), bovine pancreatic RNase A, bovine seminal RNase, human eosinophil-derived RNase and angiogenin have exhibited potent toxicity on tumor cells [138–141] (Table 2). The gene discussed is RNASE1; the disease is neoplasm.